The U.S. Justice Department and Treasury Department have announced a major crackdown on the Sinaloa cartel, with charges filed against four sons of imprisoned drug kingpin Joaquín "El Chapo" Guzmán and sanctions imposed against two Chinese companies and five people in China and Guatemala. Attorney General Merrick Garland said the charges are part of a larger effort to combat the trafficking of fentanyl coming north into the U.S. while also cracking down on the trafficking of guns going south into Mexico. The Biden administration has said it is committed to strengthening cooperation with Mexico to combat the trafficking of fentanyl and other drugs.