After 127 years of operation, Anchor Brewing Co., America's first craft brewery and a beloved staple in San Francisco, is set to close its doors due to the impacts of the pandemic, inflation, and a highly competitive market. Despite its success, the brewery has been facing increasing difficulty turning a profit in recent years due to a proliferation of canned cocktails and other craft beers. Anchor Brewing Co.'s closure marks the end of an era for craft beer in the United States.